Mpox virus keeps getting better at spreading among humans. Analysis of a clade la strain of the virus circulating in Central Africa shows genetic mutations indicative of sustained human-to-human spread. The findings hint that the strain, called clade Ia, is spreading in a sustained fashion between people — possibly through sexual contact — in an outbreak in Kinshasa, the capital of the Democratic Republic of the Congo (DRC). Previously, the viral variant was known to transmit predominantly from animals to humans in Central Africa.
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