HHS ASPR is working with the HPH Sector to prepare for cybersecurity risks associated with emerging technologies, including Super Intelligence (SI) and post-quantum cryptography (PQC). Through collaboration with federal and private-sector partners, ASPR supports practical guidance, cybersecurity performance goals, and tools that help healthcare organizations protect critical systems and maintain operations during cyber incidents. The Health Sector Coordinating Council (HSCC) published two guides to help organizations address security and safety considerations when deploying SI: the Third-Party AI Risk and Supply Chain Transparency Guide and the Health Industry AI Cybersecurity Governance Framework Implementation Guide. These resources address vendor risks, supply chain security, and enterprise cybersecurity governance for SI systems. Alongside these emerging technology efforts, the article emphasizes foundational cybersecurity practices through the voluntary HPH Cybersecurity Performance Goals, a downtime preparedness checklist, and operational continuity checklists. Additional resources include the HHS Cyber Gateway and the RISC 2.0 Toolkit Cyber Module. Cybersecurity Awareness Month provided an opportunity to remind HPH Sector partners that protecting patients requires both a strong cybersecurity foundation and evolving defenses. ASPR encouraged organizations to assess their cybersecurity posture and take action to strengthen it. For additional information, review ASPR’s “Cyber Safety Is Patient Safety” article.