On May 15, CDC issued a health update on potential risk for new mpox cases. In the United States, cases of mpox have declined since peaking in August 2022. CDC continues to receive reports of cases that reflect ongoing community transmission in the United States and internationally.
This week, CDC and local partners are investigating a cluster of mpox cases in the Chicago area. From April 17 to May 5, 12 confirmed and one probable case of mpox were reported to the Chicago Department of Public Health. All cases were among symptomatic men. No patients have been hospitalized. Nine (69%) of 13 cases were among men who had received two JYNNEOS vaccine doses. Although vaccine-induced immunity is not complete, vaccination continues to be one of the most important prevention measures. CDC expects new cases among previously vaccinated people to occur, but people who have completed their two-dose JYNNEOS vaccine series may experience less severe symptoms than those who have not.
The upcoming summer season could lead to a resurgence of mpox as people gather for festivals and other events. The Health Alert Network health update provides resources on clinical evaluation, treatment, vaccination, and testing.