On February 29, CDC released interim considerations for advanced readiness and preparedness for MPXV. This document provides state, tribal, local, and territorial (STLT) health officials with suggestions for improving readiness for managing persons with and mitigating outbreaks of Clade I MPXV within their jurisdictions.
Health officials should use these interim considerations to assess their jurisdiction’s readiness for Clade I MPXV response, identify potential response gaps, coordinate with jurisdictional response partners, and develop strategies for improving readiness, including requesting technical assistance from CDC if needed.
Currently, there is an outbreak of concern of Clade I MPXV in the Democratic Republic of the Congo. Clade I MPXV is endemic to Central Africa and has previously been observed to be more transmissible and cause more severe infection than Clade II MPXV. At this time, the risk to the United States remains low, and there are no documented cases of Clade I MPXV within the United States.